Plant Transcription Factor Database
Previous version: v3.0
Picea glauca
bZIP Family
Species TF ID Description
Pgl000101bZIP family protein
Pgl000557bZIP family protein
Pgl000721bZIP family protein
Pgl001304bZIP family protein
Pgl001752bZIP family protein
Pgl002487bZIP family protein
Pgl002713bZIP family protein
Pgl003884bZIP family protein
Pgl004666bZIP family protein
Pgl005872bZIP family protein
Pgl005885bZIP family protein
Pgl006189bZIP family protein
Pgl006983bZIP family protein
Pgl007327bZIP family protein
Pgl007843bZIP family protein
Pgl009375bZIP family protein
Pgl009389bZIP family protein
Pgl009794bZIP family protein
Pgl011432bZIP family protein
Pgl012351bZIP family protein
Pgl013977bZIP family protein
Pgl014294bZIP family protein
Pgl014347bZIP family protein
Pgl015687bZIP family protein
Pgl015744bZIP family protein
Pgl015909bZIP family protein
Pgl016280bZIP family protein
Pgl017299bZIP family protein
Pgl017605bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833